The Second Ministry of Ramachandran was the Council of Ministers, headed by M. G. Ramachandran, that was formed after the seventh legislative assembly election, which was held in two phases on the 28th and 31st of May 1980. The results of the election were announced in June 1980, and this led to the formation of the 7th Assembly. On 9 June 1980, the Council took office.

Constitutional requirement For the Council of Ministers to aid and advise Governor According to Article 163 of the Indian Constitution,

This means that the Ministers serve under the pleasure of the Governor and he/she may remove them, on the advice of the Chief Minister, whenever they want.

The Chief Minister shall be appointed by the Governor and the other Ministers shall be appointed by the Governor on the advice of the Chief Minister, and the Minister shall hold office during the pleasure of the Governor:Provided that in the States of Bihar, Madhya Pradesh and Odisha, there shall be a Minister in charge of tribal welfare who may in addition be in charge of the welfare of the Scheduled Castes and backward classes or any other work.

Cabinet ministers S.noNameDesignationPartyChief Minister1.M.G. RAMACHANDRANChief Minister (Also in charge of Home Ministry)AIADMKCabinet Ministers2.Dr. V.R. NedunchezhianMinister for FinanceAIADMK3.Panruti S. RamachandranMinister for Electricity4.K.A. KRISHNASAMYMinister for Dairy Development5.R.M. VEERAPPANMinister for Information and Religious Endowments6.C. ARANGANAYAGAMMinister for Education7.K. KALIMUTHUMinister for Agriculture8.C. PONNAIYANMinister for Law and Industries9.S. RAGHAVANANDHAMMinister for Labour10.H.V. HANDEMinister for Health11.S. MUTHUSAMYMinister for Transport12.S. THIRUNAVUKKARASUMinister for Handlooms13.S. RAJENDRANMinister for Environmental Pollution Control14.R. SOUNDARARAJANMinister for Local Administration15.S.R. ERADHAMinister for Public Works16.M.R. GOVENDANMinister for Backward Classes17.GOMATHI SRINIVASANMinister for Social Welfare18.VIJAYALAKSHMI PALANISAMYMinister for Khadi19.Y.S.M. YUSUFMinister for Irrigation and Wakf20.R. ARUNACHALAMMinister for Rural Industries21.K. KALAIMANIMinister for Fisheries22.T. VEERASWAMYMinister for Food23.K.K.S.S.R. RAMACHANDRANMinister for Co-operation

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