Aplysinellidae is a family of sponges belonging to the order Verongiida. The family was first described in 1980 by Patricia Bergquist.

Genera: Aplysinella Bergquist, 1980 Narrabeena Cook & Bergquist, 2002 Patriciaplysina Van Soest & Hooper, 2020 Suberea Bergquist, 1995

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