Tenilapine is an atypical antipsychotic which has never been marketed in the US.
Pharmacodynamics Tenilapine has a relatively high affinity for the 5-HT2A receptor, and relatively low (micromolar) affinities for dopamine receptors. + Binding affinities Receptor Ki (nM) D2 1584 D4 721±300 5-HT2A 40 The ratio of D2 to D4 bonding is similar to that of clozapine. Like many other atypical antipsychotics, it is a potent 5-HT2C antagonist.
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