Alexander Zverev defeated top seed Stefanos Tsitsipas in the final, 6–4, 7–6(7–3) to win the men's singles tennis title at the 2021 Mexican Open.
Rafael Nadal was the defending champion, but chose not to defend his title.
Seeds
Draw
Finals
Top half
Bottom half
Qualifying
Seeds
Qualifiers
Lucky loser
Qualifying draw
First qualifier
Second qualifier
Third qualifier
Fourth qualifier
References
External links Main draw Qualifying draw