Pamela Adlon has starred in many feature films, television shows, and video games. She is known for her performances in Lucky Louie (2006), Louie (2010–2015), and Better Things (2016–2022). She also has had major performances in The Facts of Life (1983–1984), Californication (2007–2014), and guest appearances in The Jeffersons (1984), Boston Legal (2007–2008), Parenthood (2012), and This Is Us (2020). She is also a well known voice artist. Her voice credits include the animated programs Bobby's World (1992–1998), Rugrats (1992–2004), Recess (1997–2001), King of the Hill (1997–2010, 2025–present), Phineas and Ferb (2010–2013), Bob's Burgers (2012–2020), and Milo Murphy's Law (2016–2019).
Live-action filmography Film + List of acting performances in feature films Year Title Role Notes 1982 Grease 2 Dolores Rebchuck 1984 Bad Manners Girl Joey 1986 SpaceCamp Girl in Launch Control Gallery Uncredited Willy/Milly Willy / Milly Niceman 1989 Say Anything... Rebecca After Midnight Cheryl Segment: "Allison's Story" 1990 The Gate II: Trespassers Liz The Adventures of Ford Fairlane Pussycat 1996 Bed of Roses Kim Sgt. Bilko Sgt. Raquel Barbella Father Frost Marphuska Two Guys Talkin' About Girls Tracy Direct-to-video 1997 Plump Fiction Vallory Cox Eat Your Heart Out Samantha Directed by 1998 Some Girl Jenn Waiting for Woody Lyza Short film 2000 Dirk and Betty Daisy Net Worth Unknown 2005 Lucky 13 Brenda 2011 Conception Tay 2013 9 Full Moons Rachel Stevens I Know That Voice Herself Documentary 2014 Truckin''' | Perri Pinkston | Short film |- | 2016 ! scope="row" | First Girl I Loved| Sharon
| 2017 ! scope="row" | I Love You, Daddy| Maggie
| rowspan="2" | 2018 ! scope="row" | All Square| Debbie
! scope="row" | Bumblebee| Sally Watson
| rowspan="2"|2020 ! scope="row" | The King of Staten Island| Gina
! scope="row" | Holler| Rhonda
| 2024 ! scope="row" | Babes'' N/A Director
Television + List of acting performances in television shows Year Title Role Notes 1982 Little Darlings Angel Bright Television film 1983–1984 The Facts of Life Kelly Affinado 12 episodes 1984 The Fantastic World of D.C. Collins Tatyana Television film Night Court Andy / Stella Episode: "Bull Gets a Kid" The Jeffersons Stevie Episode: "Try a Little Tenderness" 1984–1985 E/R Jenny Sheinfeld 3 episodes 1986 The Redd Foxx Show Toni Rutledge 7 episodes Pleasures Claudia Television film Disneyland Jesse Episode: "The Leftovers" 1988 The Bronx Zoo Lisa Episode: "Ties That Bind" ABC Afterschool Special Jill Episode: "A Family Again" 1989 Wiseguy Tanya Medley 3 episodes Star Trek: The Next Generation Oji Episode: "Who Watches the Watchers" 21 Jump Street Dori the Psychic Episode: "Old Haunts in the New Age" 1991 Life Goes On Ruth Beale Episode: "Armageddon" 1992 Down the Shore Miranda Halpern 13 episodes The Heights Rosie Episode: "Splendor in the Past" 1996 Murder One Amy Scott Episode: "Chapter Fourteen" Relativity Marcy Sedaris 2 episodes 1997 Breast Men Margaret Television film 2003 Six Feet Under Nathaniel / Isabel / Evil Nurse Episode: "Everyone Leaves" The Making of King of the Hill Herself Television documentary 2005 Unscripted Pam 4 episodes 2006 Lucky Louie Kim 13 episodes; also writer 2007 The Wedding Bells DeDe Stoller 2 episodes 2007–2008 Boston Legal Attorney Emma Path 4 episodes 2007–2014 Californication Marcy Runkle 80 episodes 2009 Monk Sarah Longson Episode: "Mr. Monk On Wheels" Ace in the Hole Susanna Morella Unsold pilot 2010 True Jackson, VP Babs Episode: "Little Buddies" 2010–2015 Louie Pamela 14 episodes; also writer and producer 2011 Love Bites Colleen Rouscher 2 episodes 2012 Parenthood Marleise Deigan 2014 Rake Glenn Shepard 2015 Playing House Pam Episode: "Celebrate Me Scones" 2016–2022 Better Things Sam Fox 44 episodes; also creator, writer, director, executive producer 2019 Young Sheldon Mrs. Wolowitz Episode: "A Swedish Science Thing and the Equation for Toast" 2020 This Is Us Dr. Leigh 4 episodes 2023 History of the World, Part II Fanny Mudman 3 episodes 2024 Elsbeth Chef Genevieve "Veev" Hale Episode: "Elsbeth Flips the Bird"; also director 2025 Mid-Century Modern Mindy Schneiderman 3 episodes Shifting Gears Molly 2 episodes
Voice-over filmography Film + List of voice performances in feature and direct-to-video films Year Title Role Notes 1992 FernGully: The Last Rainforest Fairy #2 A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information. 1997 Princess Mononoke Additional voices English dub 1998 Kiki's Delivery Service Ket English Disney dub 1999 O' Christmas Tree Baby Bear Direct-to-video 2000 Vampire Hunter D: Bloodlust Leila Gen13 Sarah Rainmaker Direct-to-video 2001 Recess: School's Out Ashley Spinelli The Trumpet of the Swan A.G. Skinner Recess Christmas: Miracle on Third StreetAshley Spinelli Direct-to-video 2003 The Animatrix Jue / Manabu Brother Bear Geese in flight formation Recess: All Growed DownAshley SpinelliDirect-to-video Recess: Taking the Fifth Grade 2004 Teacher's Pet Trevor / Taylor / Tyler 2008 Tinker Bell Vidia 2009 Tinker Bell and the Lost Treasure Uncredited2010 A Turtle's Tale: Sammy's Adventures Female Turtle #1 Tinker Bell and the Great Fairy RescueVidia2012 Secret of the Wings Dino Time Ernie FitzpatrickEnglish dub 2014 The Pirate FairyVidia Tinker Bell and the Legend of the NeverBeast 2017 Best Fiends: Boot Camp Hank Short film Best Fiends: Visit Minutia 2018 Best Fiends: Fort of Hard Knocks Bandit Slug 2019 Best Fiends: The Immortal Cockroach Hank Trouble Rousey 2023 Leo Sandy 2026 TanglesDebbie
Television