General Barnes may refer to:
Edward Barnes (British Army officer) (1776–1838), British Army lieutenant general Gladeon M. Barnes (1887–1961), U.S. Army major general James Barnes (general) (1801–1869), Union Army brigadier general and brevet major general Joseph Barnes (American physician) (1817–1883), Union Army brigadier general and brevet major general, 12th Surgeon General of the United States Army Reginald Barnes (1871–1946), British Army major general
See also Alfred Smith Barnes (1817–1888), American publisher and philanthropist known as "the General" Attorney General Barnes (disambiguation)