The Great Silence is a 1968 an Italian-French Spaghetti Western directed and co-written by Sergio Corbucci.
The Great Silence may also refer to: The Great Silence: Science and Philosophy of Fermi's Paradox, a 2018 book by Milan M. Ćirković "The Great Silence" (short story), a 2015 short story by Ted Chiang Fermi paradox or the Great Silence, the seemingly paradoxical absence of evidence for extraterrestrial intelligence, named after Enrico Fermi