Colmenero is a Spanish surname. Notable people with the surname include:
Francisco Colmenero (born 1932), Mexican voice actor and director Francisco Ferreira Colmenero (born 1967), Spanish footballer known as Patxi Ferreira José Manuel Colmenero Crespo (born 1973), Spanish footballer Juan Ruiz de Colmenero (1596–1663), Spanish bishop Alicia Diana Santos Colmenero (born 1950), Mexican voice actress