Klyne is a surname (and, more rarely, a given name). Notable people with the name include:

Surname George Klyne (1828–1875), Canadian politician; Member of the Legislative Assembly of Manitoba Marty Klyne (born 1957), Canadian senator and former corporate executive Michel Klyne (1781–1868), Canadian employee of North West Company and Hudson's Bay Company William Klyne (1913–1977), British organic chemist

Given name Klyne Snodgrass (born 1944), American theologian and author

See also Similar surnames: Clain, Clein, Cline, Clyne, Klein, Kleine, Kline