Desmond Williams may refer to:
Desmond Williams (musician), American electronica musician and record producer Desmond Williams (architect) (1932–2026), British architect Desmond Williams (bishop) (1930–2006), Irish Roman Catholic bishop Desmond Williams (boxer) (born 1967), Sierra Leonean boxer Desmond Rex Williams (born 1933), English snooker and billiards player Thomas Desmond Williams (1921–1987), Irish historian
See also Des Williams (1928–2011), South African boxer