Bedsole is a surname. Notable people with the surname include:
Ann Bedsole (1930–2025), American politician, businesswoman, community activist, and philanthropist Hal Bedsole (1941–2017), American football player Loraine Bedsole Bush Tunstall (1881–1953), American social reformer Russell Bedsole (born 1975), American politician and law enforcement officer
See also McEntyre, Alabama, an unincorporated community also known as Bedsole