Brien is a surname and male given name. Notable people with this name include:
Surname Alan Brien (1925–2008), English journalist Chris Brien, drummer, percussionist and drum clinician Don Brien (born 1959), Canadian sprint canoer Doug Brien (born 1970), American football placekicker Edward Brien (1811–1902), Archdeacon of Emly Francis Brien, pseudonym of Australian writer Hilary Lofting James Brien (1848–1907), politician and physician Jennifer Brien, American talk radio host Jerry Brien, Australian rugby league football player John Wesley Brien (1864–1949), Canadian politician and physician Jon D. Brien, American politician Kathleen Brien, also known as Katy B (born 1989), English singer and songwriter Lévis Brien (born 1955), Canadian politician Pierre Brien (born 1970), Canadian politician Raley Brien, pseudonym of American writer Johnston McCulley Robert Brien (born 1944), Australian tennis player Rory Brien (born 1991), Australian rugby league football player Timothy Brien, defendant in Varnum v. Brien Tony Brien (born 1969), Irish football player William Roy Brien (1930–1987), English football player William W. Brien (born 1957), American orthopedic surgeon
Given name Brien Best (born 1996), Barbadian weightlifter Brien Cobcroft (1934–2010), Australian equestrian Brien Cokayne, 1st Baron Cullen of Ashbourne (1864–1932), British businessman and banker Brien Cullen, American football coach Brien McIlroy (1939–1995), Scottish football player Brien McMahon (1903–1952), American lawyer and politician Brien S. Wygle (1924–2020), American pilot Brien Taylor (born 1971), American baseball player
See also O'Brien (disambiguation) Brian Bryan (disambiguation) Brayan