109th Brigade may refer to:

British India 109th Indian Infantry Brigade, a unit of the British Indian Army during World War II

Germany 109th Panzer Brigade

Spain 109th Mixed Brigade, a mixed brigade of the Spanish Republican Army in the Spanish Civil War

United Kingdom 109th Brigade (United Kingdom), a British Army formation during World War I 109th (Howitzer) Brigade, Royal Field Artillery, a British Army unit during World War I 109th Territorial Defense Brigade, a unit of the Ukrainian Territorial Defense Forces

See also 109th Division (disambiguation) 109th Regiment (disambiguation)