Senator Chambers may refer to:
Members of the United States Senate Ezekiel F. Chambers (1788–1867), U.S. Senator from Maryland from 1826 to 1834 Henry H. Chambers (1790–1826), U.S. Senator from Alabama from 1825 to 1826
United States state senate members David Chambers (congressman) (1780–1864), Ohio State Senate Ernie Chambers (born 1937), Nebraska State Senate George Chambers (New York politician) (1815–1880), New York State Senate John Green Chambers (1798–1884), Texas State Senate