George E. Chamberlain (1854–1928) was a U.S. Senator from Oregon from 1909 to 1921. Senator Chamberlain may also refer to:
Calvin T. Chamberlain (1795–1878), New York State Senate E. Kirby Chamberlain (fl. 1840s–1850s), California State Senate George Henry Chamberlain (1862–1943), Ohio State Senate Loyed Ellis Chamberlain (fl. 1890s), Massachusetts State Senate Mellen Chamberlain (1821–1900), Massachusetts State Senate Roger Chamberlain (born 1963), Minnesota State Senate Robert P. Chamberlin (born 1965), Mississippi State Senate