Obermueller or Obermüller is a surname. Notable people with the surname include:
Beni Obermüller (1930–2005), German alpine skier Georg Obermüller (1915–????), Austrian sailor Horst Obermüller, Austrian sailor Jerry Obermueller (born 1947), American politician Karola Obermueller (born 1977), German composer and teacher Mike Obermueller (born 1973), American lawyer and politician Patrick Obermüller (born 1999), Austrian footballer Wes Obermueller (born 1976), American baseball player