Novelo is a surname. Notable people with the surname include:
Cleominio Zoreda Novelo (born 1950), Mexican politician and lawyer Claudia Novelo (born 1965), Mexican synchronized swimmer Freddy Novelo (1960–2013), Mexican philanthropist and art collector Landy Berzunza Novelo (born 1965), Mexican politician Lupita Novelo (born 1967), Mexican tennis player