Novak Djokovic defeated Diego Schwartzman in the final, 7–5, 6–3 to win the men's singles tennis title at the 2020 Italian Open. It was his fifth Italian Open title and record 36th Masters 1000 title overall. Djokovic entered his 287th week as world No. 1 (surpassing Pete Sampras for the second-most of all time) following the tournament.
Rafael Nadal was the two-time defending champion, but lost to Schwartzman in the quarterfinals.
Casper Ruud became the first Norwegian to reach a Masters semifinal, surpassing his father Christian Ruud, who reached the quarterfinals of Monte Carlo in 1997.
By defeating Stan Wawrinka in the first round, Lorenzo Musetti became the first player born in 2002 to win an ATP match.
Seeds The top eight seeds received a bye into the second round.
The players who also received a bye into the second round were as follows, corresponding each semifinalist from the US Open: Pablo Carreño Busta
The other seven byes were removed and therefore seven players were added into the main draw.
Draw
Finals
Top half
Section 1
Section 2
Bottom half
Section 3
Section 4
Qualifying
Seeds
Qualifiers
Lucky loser
Qualifying draw
First qualifier
Second qualifier
Third qualifier
Fourth qualifier
Fifth qualifier
Sixth qualifier
Seventh qualifier
Eighth qualifier
References Main draw Qualifying draw