Senator Wise may refer to:
Bob Wise (born 1948), West Virginia State Senate Frank C. Wise (1864–1956), Ohio State Senate Henry A. Wise (New York state senator) (1906–1982), New York State Senate Jacob M. Wise (fl. 1820s), Pennsylvania State Senate J. J. Wise (1867–1930), Ohio State Senate Max Wise (born 1975), Kentucky State Senate Seelig Wise (1913–2004), Mississippi State Senate Stephen Wise (politician) (born 1941), Florida State Senate Thomas Dewey Wise (born 1939), South Carolina State Senate