William Henry Byrne (17 May 184428 April 1917) was an Irish architect who mainly designed churches. He studied under James Joseph McCarthy before going into business with John O’Neill in 1869. He worked on his own after O'Neill's death in 1883. In 1902, he took his son Ralph Henry Byrne into partnership, operating as "W.H. Byrne & Son".
Designs Byrne mainly designed churches, though his main Dublin work was the South City Markets in George's Street. His work included: Mary Immaculate, Refuge of Sinners Church, Rathmines, Dublin, extended (date unknown) church (designed by Patrick Byrne, 1854) Church of the Sacred Heart, the Crescent, Limerick, 1868 Design for interior of Chapel, St Patrick's College, Maynooth, entry was unsuccessful, 1888 South City Markets, South Great George's Street, 1881 Former Dockrells, South Great George's Street, Dublin, 1888 Tholsel, Drogheda, County Louth, 1890 conversion of 1770 building by George Darley into a bank Sheil Hospital, Ballyshannon, County Donegal, 1891 MacHale Memorial Church, Tubbernavine, County Mayo, 1891 Church of the Three Patrons, Rathgar, Dublin, 1891 (facade for church built from 1860 to 1862 by Patrick Byrne) Church of the Immaculate Conception, Louth, County Louth, 1892 De La Salle College Waterford, 1894 Presbytery, Roscommon, County Roscommon, 1895 Conciliation Hall, Burgh Quay, Dublin, 1897 (rebuild of 1843 building by Peter Martin as a concert hall) Holy Redeemer Church, Bray, 1898 (remodelling of 1852 church by Peter Byrne) Carmelite Abbey, Loughrea, County Galway, 1899 Church of the Assumption, Howth, 1899 Former bank, Thomas Street, Dublin, 1902 Mary Immaculate College, Limerick, 1903 St Joseph's Church, Terenure, 1904 St John's Church, Dublin Road, Kilkenny, 1907 No 58, Upper O'Connell Street, Dublin, 1922 (date rebuilt)
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