William Gamble may refer to: William Gamble (general) (1818–1866), U.S. Army cavalry officer who fought at the Battle of Gettysburg William Gamble (business) (1805–1881), Canadian merchant, miller, and pioneer William R. Gamble (1850–1910), civil rights activist and barber in Nebraska William Gamble (cricketer) (1798–1855), English cricketer William Gamble of Procter and Gamble, son of James Gamble, co-founder of Procter and Gamble

See also William Gambel (1823–1849), U.S. naturalist and collector