Brugnoli is a surname. Notable people with the surname include:
Amalia Brugnoli (1802–1892), Italian ballerina Annibale Brugnoli (1843–1915), Italian painter Attilio Brugnoli (1880–1937), Italian composer, pianist and musicologist Emanuele Brugnoli (1859–1944), Italian painter and engraver Patrick Brugnoli (born 1970), Italian ice hockey player Renato Brugnoli (born 1969), Swiss footballer