Houblon is a surname. Notable people of this surname include:

Abraham Houblon (1640–11 May 1722), Governor of the Bank of England, brother of James and John Sir James Houblon (1629–1700), MP, Director of the Bank of England, brother of Abraham and John Sir John Houblon (1632–1712), first Governor of the Bank of England, brother of Abraham and James Jacob Houblon (1710–1770), MP

John Archer-Houblon (1773–1831), MP, descendant of the Bank of England Houblons Thomas Archer Houblon (1849–1933), Archdeacon of Oxford

See also Houblon's Almshouses, Richmond Houblon Apartments, part of the Relay Building, Whitechapel, London