The 2021–22 Liga IV was the 80th season of Liga IV and the 54th since the 1968 administrative and territorial reorganization of the country, representing the fourth tier of the Romanian football league system. The champions of each county association played against one from a neighbouring county in a play-off for promotion to Liga III.

The counties were divided into seven regions, each consisting of six counties and the draw was made on 24 February 2022.

County leagues

North–East Bacău (BC) Botoșani (BT) Iași (IS) Neamț (NT) Suceava (SV) Vaslui (VS)

North–West Bihor (BH) Bistrița-Năsăud (BN) Cluj (CJ) Maramureș (MM) Satu Mare (SM) Sălaj (SJ)

Center Alba (AB) Brașov (BV) Covasna (CV) Harghita (HR) Mureș (MS) Sibiu (SB)

West Arad (AR) Caraș-Severin (CS) Gorj (GJ) Hunedoara (HD) Mehedinți (MH) Timiș (TM)

South–West Argeș (AG) Dâmbovița (DB) Dolj (DJ) Olt (OT) Teleorman (TR) Vâlcea (VL)

South Bucharest (B) Călărași (CL) Giurgiu (GR) Ialomița (IL) Ilfov (IF) Prahova (PH)

South–East Brăila (BR) Buzău (BZ) Constanța (CT) Galați (GL) Tulcea (TL) Vrancea (VN)

Promotion play-off The matches were played on 18 and 25 June 2022.

| colspan=3 bgcolor=97DEFF | Region 1 (North-East) | colspan=2 bgcolor=97DEFF | ||5–0||1–4 ||0–0||0–1 ||3–3||3–4 |- | colspan=3 bgcolor=97DEFF | Region 2 (North-West) | colspan=2 bgcolor=97DEFF | ||0–3||0–2 ||w/o||w/o ||1–1||0–3 |- | colspan=3 bgcolor=97DEFF | Region 3 (Center) | colspan=2 bgcolor=97DEFF | ||4–1||6–3 ||1–1||2–1 ||11–2||7–1 |- | colspan=3 bgcolor=97DEFF | Region 4 (West) | colspan=2 bgcolor=97DEFF | ||2–0||2–0 ||5–0||6–2 ||4–1||0–0 |- | colspan=3 bgcolor=97DEFF | Region 5 (South-West) | colspan=2 bgcolor=97DEFF | ||3–1||0–2 ||1–0||1–1 ||1–1||0–1 |- | colspan=3 bgcolor=97DEFF | Region 6 (South) | colspan=2 bgcolor=97DEFF | ||3–2||1–3 ||0–1||3–1 ||2–3||0–1 |- | colspan=3 bgcolor=97DEFF | Region 7 (South-East) | colspan=2 bgcolor=97DEFF | ||5–2||0–1 ||2–1||0–4 ||w/o||w/o

League standings Alba County Team changes from the 2019–20 season CS Ocna Mureș achieved promotion to the 2020–21 Liga III. Industria Galda was relegated from 2020–21 Liga III. AFC Micești and Nicolae Linca Cergău withdrew. Navobi Alba Iulia merged with GT Sport Alba Iulia, being absorbed by the second one. Hidromecanica Șugag, Kinder Teiuș and Târnavele Tiur were admitted upon request.

Arad County Team changes from the previous season Frontiera Curtici achieved promotion to the Liga III. UTA Arad II withdrew. Podgoria Pâncota, CS Beliu and CS Glogovăț were reinstated from 2019–20 season.

Championship play-off The championship play-off was played in a double round-robin tournament between the best four teams of the regular season. The teams started the play-off with half of the points accumulated in the first stage of the season.

Championship play-out The championship play-out was played in a single round-robin tournament between the teams ranked 5–10 in the regular season. The teams started the play-out with half of the points accumulated in the first stage of the season.

Argeș County Team changes from the 2019–20 season Voința Budeasa achieved promotion to the 2020–21 Liga III. Real Bradu was promoted to 2021–22 Liga III following the 2020–21 short tournament. Muscelul Lerești (North Series winners), Speed Academy Pitești (Center Series runners-up) and Energia Stolnici (Series South winners) were promoted from the 2019–20 Liga V Argeș. Viitorul Bârla (Center Series winners) was promoted from the 2020–21 Liga V Argeș. Muscelul Câmpulung was renamed Inter Câmpulung in the summer of 2020. Juventus Bascov was renamed Juventus Victoria 1992 Bascov. Vulturii Priboieni, AS Colibași, Gloria Berevoești, FC Argeș Pitești II, Basarabi Curtea de Argeș, CS Recea, Aripi Pitești and FC Dănuț Coman withdrew. ACS Bălilești was admitted upon request.

Bacău County Team changes from the 2019–20 season Dinamo Bacău achieved promotion to the 2021–22 Liga III following the 2020–21 short tournament. AS Căiuți was renamed Viitorul Căiuți. Viitorul Curița entered in partnership with CSȘ Onești and was renamed Viitorul Curița/CSȘ Onești. FCM Bacău, Siretul Bacău, Aripile Cleja, Voința Oituz, Gloria Zemeș, CS Dofteana withdrew. Unirea Bacău, Siretu Săucești, Dinamo Bacău II, Viitorul Berești-Tazlău, Sportul Onești, Voința Brătești and Măgura Târgu Ocna were admitted upon request. Series I

Series II

Championship play-off The first two teams in each series of the regular season will meet once (3 matches per team). The teams start the Championship play-off with the points from the regular season accumulated with the teams ranked 1–9.

Bihor County Team changes from the 2019–20 season CA Oradea achieved promotion to the 2020–21 Liga III. Slovan Valea Cerului (Series I winners) was promoted from the 2019–20 Liga V Bihor. CSO Ștei, CSC Sânmartin II and CS Mădăras withdrew. CA Oradea II, Izvorul Cociuba Mare, Victoria Avram Iancu and Voința Ciumeghiu were admitted upon request. Unirea Livada was renamed Nojorid Livada. Series I (North)

Series II (South)

Championship play-off The championship play-off was played between the first two teams from each series of the regular season in a double round-robin tournament and with no records from the regular season.

Championship play-out The teams ranked 3rd to 8th in each series were played another round (5 matches) while maintaining the accumulated records. Series I (North)

Series II (South)

Bistrița-Năsăud County Team changes from the 2019–20 season Voința Mărișelu, Săgeata Dumbrăvița, Real Teaca, Silvicultorul Maieru, Heniu Leșu, Minerul Rodna, Someșul Feldru and Someșul Reteag continued from the previous season. Progresul Năsăud, Atletico Monor, Voința Livezile, Progresul Tăure, Hebe Sângeorz-Băi, Eciro Forest Telciu and Someșul Rebrișoara withdrew. ACS Dumitra withdrew during the previous season. Venus Negrilești and Sportul Beclean were admitted upon request.

Championship play-off The championship play-off was played in a single round-robin tournament between the best four teams of the regular season. The teams started the play-off with the points and goal difference carried over from the regular season.

Botoșani County Team changes from the 2019–20 season Dante Botoșani achieved promotion to the 2020–21 Liga III. Viitorul Albești, Independentul Darabani, Unirea Săveni, Flacăra Văculești, Rapid Ungureni and Sportivul Trușești withdrew. Șoimii Bălușeni, Nord Star Pomârla, Viitorul Broscăuți, Sporting Darabani and Unirea Stăuceni were admitted upon request. TransDor Tudora was renamed Partizanul Tudora.

Brașov County Team changes from the 2019–20 season Corona Brașov was promoted to 2020–21 Liga III. Carpați Berivoi withdrew during the previous season. Precizia Săcele, AFC Hărman and Cetatea Homorod withdrew. Weidenbach Ghimbav, Bucegi Moieciu, CSM Făgăraș and ACS Hoghiz were admitted upon request.

Brăila County Team changes from the 2019–20 season Sportul Chiscani achieved promotion to the 2020–21 Liga III. Voința Plopu, Pandurii Tudor Vladimirescu, Dacia Unirea Brăila II and Dinamic Unirea withdrew. Daous Dava 2018 Brăila was admitted upon request.

Championship play-off In the championship play-off each team plays every other team twice. Teams start the play-off round with their points from the regular season halved, rounded upwards, and no other records carried over from the regular season.

Championship play-out In the championship play-out each team plays every other team twice. Teams start the play-out round with their points from the regular season halved, rounded upwards, and no other records carried over from the regular season.

Bucharest Team changes from the 2019–20 season Steaua București achieved promotion to the 2020–21 Liga III. Rapid București II, Bucharest United, Comprest GIM București, Power Team București, AFC Rapid București, Electrica București, Unirea Politehnica București and Victoria București withdrew. Dinamo București, Știința București, Daco-Getica București, Sportul D&A București, Dan Chilom București, Pro Team București and Metropolitan Fotbal & Motor Club București were admitted upon request.

Championship play-off The championship play-off was played in a single round-robin tournament between the best four teams of the regular season. Depending on the place occupied in the regular season, the teams started the play-off with the following points: 1st place – 3 points, 2nd place – 2 points, 3rd place – 1 point, 4th place – 0 points. All matches were played at Romprim Stadium in Bucharest on 21, 28 May and 4 June 2022.

Buzău County Team changes from the 2019–20 season CSM Râmnicu Sărat achieved promotion to the 2020–21 Liga III. Avântul Zărnești, Locomotiva Buzău, Diadema Gherăseni, Recolta Blăjani and Înfrățirea Zoița withdrew. Pescărușul Luciu, Energia Clondiru, Voința Balta Albă, Metalul Buzău II, CSM Râmnicu Sărat II, Știința Cernătești and Progresul Beceni were admitted upon request. Fortius-Partizanul Merei was renamed Partizanul Merei. Series I

Series II

Championship play-off The championship play-off was played between the best four teams from each series of the regular season. Depending on the place occupied in the regular season, the teams started the play-off with the following points: 1st place - 3 points, 2nd place - 2 points, 3rd place - 1 point, 4th place - 0 points.

Championship play-out Depending on the place occupied in the regular season, the teams started the play-out with the following points: 5th place - 5 points, 6th place - 3 points, 7th place - 2 points, 8th place - 1 point, 9th place - 0 points.

Caraș-Severin County Team changes from the 2019–20 season Progresul Ezeriș achieved promotion to the 2020–21 Liga III. Voința Lupac achieved promotion to the 2021–22 Liga III following the 2020–21 short tournament. Metalul Bocșa, Croația Clocotici, Steaua Prigor, Ad Mediam Mehadia, Era S Comexim Caransebeș, Agmonia Zăvoi and Bistra Glimboca withdrew. Banatul Ocna de Fier, Recolta Rafnic and Mundo Reșița were admitted upon request. Șoimii Oțelu Roșu was renamed CS Oțelu Roșu.

Călărași County Team changes from the 2019–20 season season CSM Oltenița achieved promotion to the 2020–21 Liga III. Viitorul Curcani and Vulturii Gălbinași withdrew. Progresul Perișoru, Rapid Ulmeni and Șoimii Progresu were admitted upon request. Series A

Series B

Championship play-off The teams started the play-off with all the records from the regular season. Series A

Series B

Championship play-out The teams started the play-out with all the records from the regular season. Series A

Series B

Championship final

Venus Independența won the Liga IV Călărași County and qualified for the promotion play-off in Liga III.

Cluj County Team changes from the 2019–20 season Someșul Dej joined to 2020–21 Liga III benefiting from the withdrawal of Voința Budeasa. CSM Câmpia Turzii and CFR Dej withdrew. Viitorul Poieni, Someșul Dej II and Academia Florești were admitted upon request.

Constanța County Team changes from the 2019–20 season Gloria Albești achieved promotion to the 2020–21 Liga III. Poseidon Limanu-2 Mai and CS Medgidia withdrew during the 2019–20 Liga III. Axiopolis Cernavodă withdrew at the end of the 2020–21 Liga III season and took the place of its second team, Axiopolis Cernavodă II. Viitorul Fântânele, CS Lipnița-Carvăn and CS Eforie withdrew. Viitorul Hârșova and Viitorul Cobadin were admitted upon request. CS Cumpăna was renamed Victoria Cumpăna.

Covasna County Liga IV Covasna was held with only nine teams in the first season after the COVID-19 pandemic — eight from the previous season and one newly admitted team. The competition was played in a single round-robin format.

Team changes from the 2019–20 season Sepsi Sfântu Gheorghe II enrolled in the 2020–21 Liga III upon request. Venus Ozun was admitted upon request.