Slusser is a surname. Notable people with the surname include:
George Edgar Slusser (1939–2014), American scholar, professor, and writer James Slusser (1916–1996), American police officer Jean Paul Slusser (1886–1981), American painter, designer, art critic, and professor Lewis Slusser (1820–1892), American politician and physician Mary Shepherd Slusser (1918–2017), American archaeologist Susan Slusser (born 1967), American sportswriter