Pryke is a surname. Notable people with the surname include:
Anne Pryke, Jersey politician Clement Pryke (born 1968), English-American physicist Paula Pryke (born 1960), British florist and author Richard Pryke, British sound engineer Roger Pryke (1921–2009), Reforming priest, social activist, civil servant Sarah Pryke, behavioral and evolutionary ecologist
See also Pryke baronets