Daniello is both a masculine Italian given name and a surname. Notable people with the name include:
Given name Daniello Bartoli (1608–1685), Italian Jesuit writer and historiographer Daniello Concina (1687–1756), Italian Dominican preacher, controversialist and theologian Daniello Marco Delfino (1653–1704), Italian cardinal Daniello Porri (died 1566), Italian Renaissance painter Daniello Solaro, Italian Baroque sculptor
Surname Joe Daniello, American animation director Ralph Daniello (1886–1925), American mobster