Saint Louis River or Saint-Louis River may refer to:
Canada Saint-Louis River (Yamaska River tributary), a tributary of the Yamaska River in Quebec Saint-Louis River (Beauharnois), a tributary of the Saint Lawrence River in Quebec Saint-Louis River (Du Loup River tributary) (see List of rivers of Quebec#North shore of St Lawrence river – between Repentigny and Trois-Rivières) Saint-Louis River (Valin River tributary), a tributary of the Valin River in Quebec Rivière de Grand-Saint-Louis, a tributary of the Gentilly River South-West in Quebec
United States Saint Louis River (Lake Superior tributary)
Guadeloupe Rivière de Saint-Louis, a river on the island of Marie-Galante