St. Louis High School may refer to:
St. Louis Senior High School (Ghana), Kumasi, Ashanti Region St Louis High School, Rathmines, Dublin, Ireland St. Louis Catholic High School, Lake Charles, Louisiana, US Saint Louis School, Honolulu, Hawaii, US St. Louis 1 Catholic High School Surabaya, East Java, Indonesia
See also St. Louis University High School, St. Louis, Missouri, US :Category:High schools in St. Louis, for other high schools in St. Louis, Missouri, US