Anguiano is a surname originating in Spain. Notable people with the surname include:
Armando Ayala Anguiano (1928–2013), independent journalist, historian, editor, entrepreneur and novelist Carlos Anguiano (born 1999), American professional soccer player Eduardo Montagner Anguiano, Chipilo Venetian writer Humberto Anguiano (born 1910, date of death unknown), Mexican modern pentathlete Karen Quiroga Anguiano (born 1980), Mexican politician Lupe Anguiano (born 1929), Mexican-American civil rights activist Mario Anguiano Moreno (born 1962), Mexican politician and Governor of Colima from 2009 to 2015 Raúl Anguiano (1915–2006), Mexican painter Sergio Salvador Aguirre Anguiano (1943–2020), Mexican jurist and Associate Justice of the Supreme Court of Justice of the Nation
See also Anguiano, a small town in the province of La Rioja, Spain Comarca de Anguiano, a comarca in La Rioja province in Spain