Sissa may refer to:
People Giulia Sissa (born 1954), Italian classical scholar and historian of philosophy Sissa (mythical brahmin), legendary Indian inventor of chess
Places Sissa Trecasali, a comune in Parma, Emilia-Romagna, Italy Sissa, Sissa Trecasali, a frazione Sissa River, Flores, East Nusa Tenggara, Indonesia
Other SISSA (International School for Advanced Studies), Trieste, Italy
See also Sessa (disambiguation)