The 1949 Challenge Desgrange-Colombo was the second edition of the Challenge Desgrange-Colombo. It included ten races: all nine races from the 1948 edition were retained and the Tour de Suisse added. The competition was won by Fausto Coppi of the Bianchi–Ursus who won four of the ten rounds: Milan–San Remo, the Giro d'Italia, the Tour de France and the Giro di Lombardia.
Races DateRaceCountryWinnerTeamReport19 MarchMilan–San Remo Report10 AprilTour of Flanders Report13 AprilLa Flèche Wallonne Report17 AprilParis–Roubaix and /Stella–DunlopReport24 AprilParis–Brussels/ Report15 MayParis–Tours Report21 May – 12 JuneGiro d'Italia Report30 June – 24 JulyTour de France ItalyReport30 July – 6 AugustTour de Suisse WolfReport23 OctoberGiro di Lombardia Report
Final standings
Riders Cyclist Team Points1 2032= 1152= 1154 685 676 627 598 599 5610 55
Nations NationPoints187826283621
References