Wayne Johnson may refer to:
Wayne Johnson (musician) (born 1949), American jazz and acoustic guitarist Wayne Johnson (Minnesota politician), American politician in Minnesota Wayne Johnson (New Mexico politician), American politician in New Mexico Wayne Johnson (Wyoming politician) (1942–2020), American politician in Wyoming Wayne Johnson (runner) (1902–1982), American long-distance runner
See also Dewayne Johnson, plaintiff in Johnson v. Monsanto Co. Dwayne Johnson, American actor and professional wrestler