Rathborne is a surname. Notable persons with the surname include:
Aaron Rathborne (fl. 1605–1622), English surveyor Basil Rathbone (1892–1967), English actor Joseph Rathborne (1807–1842), English priest Luke Rathborne, musician St George Henry Rathborne (1854–1938), American writer Tina Rathborne (born 1950), American film director and screenwriter