Senator Byrne may refer to:
Bradley Byrne (born 1955), Alabama State Senate Frank M. Byrne (1858–1927), South Dakota State Senate Gary Byrne (politician) (fl. 2020s), Indiana State Senate Hugh Byrne (Fianna Fáil politician) (born 1943), Irish Fianna Fáil Senator John F. Byrne Sr. (1911–1965), Pennsylvania State Senate John F. Byrne Jr. (born 1935), Pennsylvania State Senate Leslie Byrne (born 1946), Virginia State Senate Maria Byrne (born 1967), Irish Fine Gael Senator Paul L. Byrne (1910–1962), California State Senate Robert Byrne (North Dakota politician) (1886–1967), North Dakota State Senate William T. Byrne (1876–1952), New York State Senate
See also Harry T. Burn (1895–1977), Tennessee State Senate Senator Byrnes (disambiguation)