Smuts is an Afrikaans surname most commonly associated with Jan Smuts (1870–1950), a South African statesman, military leader and prime minister of the Union of South Africa. Other notable people with the surname include:

Barbara Smuts (born 1950), American anthropologist Dave Smuts (David, flor. 1980–2023..), Namibian Supreme Court judge Dene Smuts (1949–2016), South African politician JJ Smuts (Jon-Jon Trevor, born 1988), South African cricketer J. J. L. Smuts (Johannes Joachim Lodewyk, 1785–1869), South African public official John Christopher Smuts (1910–1979), known as Christopher Smuts, South African-born British politician Kelly Smuts (born 1990), South African cricketer Lulama Smuts Ngonyama (born 1952), known as Smuts Ngonyama, South African politician Neil Smuts (1898–?), South African aviator Olive Smuts-Kennedy (1925–2013), New Zealand politician Tobias Smuts (1861–1916), Boer war Boer general

See also Smut (disambiguation)