Prudhoe is a town in Northumberland, England.

Prudhoe may also refer to:

Related to Prudhoe, England Prudhoe Castle Algernon Percy, 4th Duke of Northumberland (1792–1865), known as Lord Prudhoe between 1816 and 1847 Prudhoe Town F.C., football club Prudhoe railway station, railway station on the Tyne Valley line

Related to Prudhoe Bay, Alaska Prudhoe Bay, Alaska, a census-designated place (CDP) in Alaska Deadhorse Airport, also known as Prudhoe Airport Prudhoe Bay Oil Field, oil field on Alaska's North Slope Prudhoe Bay oil spill, a 2006 oil spill BP Prudhoe Bay Royalty Trust, New York-based owners of the oil field

People with the surname Prudhoe Lord Prudhoe (see above) Mark Prudhoe (born 1963), English football goalkeeper William Prudhoe (1832–1908), mayor of Christchurch, New Zealand

Other Prudhoe Lions, pair of Ancient Egyptian monumental sculptures