YSS is Young–Simpson syndrome, a rare congenital disorder.

YSS may also refer to:

Groups, organizations Yayasan Sukarelawan Siswa (), Ministry of Higher Education (Malaysia) Yogoda Satsanga Society of India, a non-profit nonsectarian spiritual organization Yorkshire Subterranean Society, a caving club Young Scottish Socialists, the youth wing of the Scottish Socialist Party

Places Yengema Secondary School, Sierra Leone Yishun Secondary School, Singapore

Other uses Yessan-Mayo language (ISO 639 language code yss), a language found in Papua New Guinea Yi Sun-sin, 16th century Korean admiral

See also

YS (disambiguation) for the singular of YSs