Moriguchi (written: lit. "forest mouth/entry") is a Japanese surname. Notable people with the surname include:

Denise Moriguchi (born 1976), American businesswoman , Japanese businessman , Japanese singer , Japanese textile artist , Japanese textile artist , American businesswoman , Japanese figure skater , American businessman and activist , Japanese actress , Japanese golfer

See also Tomoko Moriguchi-Matsuno (born 1945), American businesswoman