Buffalo Creek is a long 4th order tributary to Reedy Fork in Guilford County, North Carolina.

Variant names According to the Geographic Names Information System, it has also been known historically as: South Buffalo Creek

Course Buffalo Creek is formed at the confluence of South and North Buffalo Creeks in Guilford County about 2 miles north of McLeansville, North Carolina. Buffalo Creek then flows northeast to meet Reedy Fork about 6 miles south of Osceola.

Watershed Buffalo Creek drains of area, receives about 45.5 in/year of precipitation, has a topographic wetness index of 439.98 and is about 19% forested.

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