Mukhametshin () is a Russian Tatar surname. The feminine form is Mukhametshina (). Among those with this name are:
Farid Mukhametshin (b. 1947), politician, former Prime Minister of Tatarstan Farit Mukhametshin (b. 1947), politician and diplomat Igor Mukhametshin (b. 1963), naval officer Ruslan Mukhametshin (b. 1981), footballer and coach Rustem Mukhametshin (b. 1984), footballer