Prehn is a surname. Notable people with the surname include:
Anette Prehn (born 1975), Danish author and sociologist Fred Prehn (1860-1932), American harnessmaker and merchant Kelly England Prehn (born 1988), British model, editor, influencer, fashion ambassador, and businesswoman Paul Prehn (1892–1973), American wrestler Rasmus Prehn (born 1973), Danish politician Thomas Prehn (born 1961), American cyclist