Issoufou is a surname and given name. Notable people with the surname include:
Given name Issoufou Assoumane, Nigerien politician and ministers of council Issoufou Boubacar Garba (born 1990), Nigerien footballer Issoufou Dayo (born 1991), Burkina Faso footballer Issoufou Habou (born 1945), Nigerien light-middleweight boxer Issoufou Saidou-Djermakoye (1920– 2000), Nigerien politician Issoufou Sidibé, Nigerien labour leader and politician Ousmane Issoufou Oubandawaki (born 1948), Nigerien politician
Surname Abdoul Razak Issoufou (born 1994), Nigerien taekwondo practitioner Alhassane Issoufou (born 1981), Nigerien footballer Aissata Issoufou Mahamadou, Nigerien chemist, chemical engineer, mining specialist, healthcare advocate and First Lady of Niger Boubacar Idrissa Issoufou (born 197), Nigerien footballer Lalla Malika Issoufou (born 1975), Nigerien medical doctor, patron of many charities and First Lady of Niger Mahamadou Issoufou (born 1952), Nigerien politician, President of Niger Yanis Issoufou (born 2006), French footballer
See also Issouf, a cognate