Spangenberg is a surname. Notable people with the surname include:
August Gottlieb Spangenberg (1704–1792), German theologian and minister Bill Spangenberg (active 1947–1962), bass singer in the Buffalo Bills barbershop quartet Cory Spangenberg (born 1991), American baseball player Craig Spangenberg (1914–1998), American trial attorney Cyriacus Spangenberg (1528–1604), German theologian and historian Detlev Spangenberg (born 1944), German politician Doug Spangenberg (born 1975), American music video director and documentary film maker Evgeni Pavlovich Spangenberg (1898–1968), Soviet ornithologist Frank Spangenberg (born 1957), American game show contestant George Spangenberg (1912–2000), American aircraft designer Hugo Spangenberg (born 1975), Argentine chess grandmaster Jeff Spangenberg (active from 1991), American video game producer and entrepreneur Johannes Ernst Spangenberg (1755–1814), American fraktur artist Karl Spangenberg, American engineer Marco Spangenberg (born 1980), German sport shooter who competed in the 2004 Summer Olympics Theunis Spangenberg (born 1983), South African golfer Trevor Spangenberg (born 1991), American professional soccer player