Cofie is a surname. Notable people with the surname include:

Ethel Delali Cofie, Ghanaian IT professional, entrepreneur and consultant Isaac Cofie (born 1991), Ghanaian footballer Jacob Cofie (born 2006), American basketball player Joe Cofie (born 1946), Ghanaian boxer John Cofie (born 1993), Ghanaian-born British footballer

See also Coffee (disambiguation) Coffey (disambiguation) Coffie, a surname