Yaakov Yitzchak Horowitz may refer to:

Yaakov Yitzchak of Lublin (c. 1745 – 1815), Polish rabbi known as the "Seer of Lublin" Yaakov Yitzchak Horowitz (American rabbi) (born 1956), American rabbi associated with the Manischewitz kosher food company See also Yakov Horowitz, Orthodox rabbi, author and educator from New York