Palko or Palkó is an Eastern European surname and male given name. Notable people with this name include:
Christian Palko, better known as Cage (rapper) (born 1973), American rapper and actor Dávid Palkó (born 1989), Hungarian football player Franz Xaver Palko (1724-1767), Silesian painter Fruzsina Palkó (born 1992), Hungarian handball player Jiří Palko (1941–2014), Czech rower Palkó Dárdai (born 1999), German-Hungarian football player Tyler Palko (born 1983), American football player Vladimír Palko (born 1957), Slovak politician