The 1950–51 Macedonian Republic League was the seventh since its establishment. Rabotnik Bitola won their second championship title.
Participating teams Club City Borec Kumanovo Bregalnica Shtip Crvena Dzvezda Veles Kozhuf Gevgelija Ohrid Ohrid 11 Oktomvri Kumanovo Pitu Guli Krushevo Pobeda Prilep Rabotnik Bitola Sloga Skopje SSK Skopje Skopje Tikvesh Kavadarci
Final table
References Karovski, Ilija (1996) FK Tikvesh 1930–1995 p. 35, 36
External links SportSport.ba Football Federation of Macedonia