Portocarrero is a surname. Notable people with the surname include:
Anastasio Somoza Portocarrero (born 1951), Nicaraguan heir, colonel and businessman Claudia Portocarrero (born 1985), Peruvian cumbia dancer Hope Portocarrero (1929–1991), First Lady of Nicaragua Juan Portocarrero (died 1631), Spanish Roman Catholic prelate Luis Antonio Tomás de Portocarrero (1649–1723), Spanish noble and Viceroy of Catalonia Hermenegildo Portocarrero, Baron of Forte de Coimbra (1818–1893), Brazilian nobleman and military officer, marshal in the Brazilian Army Luisa Portocarrero (born 1976), Guatemalan artistic gymnast Martina Portocarrero (1949–2022), Peruvian folk singer, cultural researcher, politician Pedro Portocarrero (disambiguation): Pedro Portocarrero (archbishop of Granada) (died 1526), Spanish Roman Catholic bishop Pedro Portocarrero (bishop, died 1600), Spanish Roman Catholic bishop Pedro Portocarrero (footballer) (born 1977), Colombian football player René Portocarrero (1912–1985), Cuban artist