__NOTOC__ Murillo is a Spanish surname. Notable people with the name include:

Ander Murillo (born 1983), Spanish footballer Bartolomé Esteban Murillo (1617–1682), Spanish artist Catalina Murillo Valverde (born 1970), Costa Rican writer Jeison Murillo (born 1992), Colombian footballer Jesús Murillo Karam (born 1947), governor of Hidalgo and attorney-general of Mexico Juan Murillo (born 1982), Venezuelan road cyclist Manuel Murillo Toro (1816–1880), Colombian president and writer Marino Murillo (born 1961), Cuban communist official Mario Murillo (footballer) (1927–2012), Costa Rican footballer Mario A. Murillo, American journalist, public radio personality, author, and academic Óscar Murillo (born 1988), Colombian footballer Oscar Murillo (artist) (born 1986), Colombian artist Pedro Domingo Murillo (1757–1810), independentist leader of Bolivia (1696–1753), Spanish Jesuit and cartographer of the Philippines Soledad Murillo (born 1956), Spanish academic and politician Teddy Murillo (died 2010), Belizean shooting victim